Our new paper is out – on new structural insights into rice KAI2 receptor and functional implications for perception and signal transduction. Published in Published in Journal of Biological Chemistry: Guercio, AM., Gilio, AK., Pawlak, J., and Shabek, N. (2024). LINK
Congratulations to Katherine Hand, our PhD student, for receiving the 2024 Summer Graduate Student Researcher Award! 🥇 This award supports graduate research in engineering, computer sciences, and disciplines with engineering-related applications and methods. Additionally, Katherine has been selected to receive the NIH eMCB T32 training grant! We are proud of you, Katherine. Well done!…Read More
Congratulations to Darian DeBortoli, Shabek Lab undergraduate researchers, have been awarded the 2024 College of Biological Science Undergraduate Researcher Summer Fellowship! Well deserved!
Congratulations to Katherine Hand (our PhD student), for receiving the 2024 Elsie Taylor Stocking Memorial Fellowship!!! The Stocking Memorial Fellowship supports outstanding graduate students in studies and research in plants. We’re proud of you Katherine!
Congratulations to the Shabek Lab especially Angelica and Fuai – Our NSF funded research with Dudareva group at Purdue University is now published in Science – more discoveries on KAI2 signaling pathway:Volatile communication in plants relies on a KAI2-mediated signaling pathway.
Our new paper on new role of the C-terminal of SCF-D3/MAX2 ubiquitin ligase in KAI2-mediated signaling. Published in New Phytologist: Tal, L., Guercio, AM., Varshney, K., Young, A., Gutjahr, C., and Shabek, N. (2023). LINK
Congratulations, Angelica!!! The recipient of the 2023 Dean’s Grad Students Mentoring Award. For her outstanding devotion to train & mentor undergrads and junior researchers in the lab.
Congratulations to Dr. Lior Tal, one of our lab’s first postoctoral fellows (since 2019), for landing a PI/Assistant Professor position and will start the Tal Lab at Tel Aviv University (Plant Sciences) in Israel! Proud of you, well done and good luck, Lior!
Congratulations to the Shabek lab (Fuai and Malathy) recent publication – our Cover Page (credits to Dr. Shabek:-) has been selected as the cover page for September 2022 Volume of Journal of Structural Biology.
Congratulations!!! The Shabek lab just received a huge grant from the Department of Energy (DOE) – Biological and Environmental Research (BER) division. This funds will support our lab in collaboration with Justin Walley group (Iowa State U) and Andrew Groover (USDA Forest Services) to investigate the ubiquitin system in trees and drought response using multiomics…Read More
Katherine Hand and Dr. Nitzan Shabek’s new paper is now published in International Journal of molecular Sciences. We highlighted recent studies that reveal new function of E3 ubiquitin ligases and their roles in chloroplast function.
Congratulation on new funded project!!! Together with Natalia Doudareva from Purdue University, Dr. Shabek received $1.5M to study new hormone-like pathway. This would be our third NSF Award in two years!!
Congratulations to Drs. Fuai Sun and Malathy Palayam for the new publication in Journal of Structural Biology. This study takes a leap towards the understanding of the molecular architecture of catalytically inactive plant β-Amylase (BAM) proteins that play an essential role in growth, development, stress response, and hormone regulation.
Congratulations!!! Natalie Hamada has won the 2022-2023 Summer Graduate Student Researcher (GSR) Fellowship Award . Natalie will continue her PhD studies on the function of ubiquitin ligase in plant immunity, and will initiate the development of advanced integrated computational strategy to study protein-small molecule interactions using Virtual Reality tools.
Congratulations Katherine! For receiving Honorable Mention – Chancellor’s Award for Excellence in Undergraduate Research – in recognition of her excellent work as Undergraduate Researcher.
New research from the Shabek laboratory at UC Davis unravels a new regulatory function of ubiquitin ligase in plant signalling. We combined structural biology, biochemistry and in planta CRISPR/Cas9 genome editing to show that the conformational switch in ASK1-D3/MAX2 CTH directly regulates the ubiquitin-mediated protein degradation process in strigolactone signaling pathway. We have also uncovered…Read More
Congratulations to Katherine Hand and Shelly Lee, Shabek Lab undergraduate researchers, have been awarded the 2022 College of Biological Science Undergraduate Researcher Summer Fellowship!
New research led by the Shabek laboratory at UC Davis together with multiple groups from Université Paris-Saclay and Technical University of Munich, revealed how molecular smoke detectors adapted to sense growth hormones in plants. https://www.nature.com/articles/s42003-022-03085-6 Highlighted in the news: UC Davis News EurekaAlert AAAS NSF Research News
Congratulations to Angelica Guercio (our PhD student), for receiving the Stocking Fellowship!!! The Elsie Taylor Stocking Memorial Fellowship supports outstanding graduate students in studies and research in plants.
Dr. Shabek has been nominated and selected to receive the 2021 Arthur C. Neish Young Investigator Award from the Phytochemical Society of North America. The Neish Awards are given each year by the PSNA to outstanding early career scientists. Congratulations, Nitzan!!!
Congratulations!!! Our lab PI, Prof. Nitzan Shabek, has just awarded with the NSF most prestigious award, The NSF CAREER. This will help to fund our research for the next 5 years including innovative initiative in promoting STEM education. The NSF CAREER is described by the NSF as supporting those with the “potential to serve as…Read More
In a new study, published in Communications Biology (Nature press), the Shabek lab determined the molecular structure of light activated sensory domain of cryptochrome-2. This work was discussed in the press - UC Davis News & Aggie News & Eureka (AAAS) Science Times & Science Daily
Dr. Nitzan Shabek, UC Davis, received the NSF EAGER award ($300,000). Together with Dr. Dinesh-Kumar's lab, they will study the molecular interactome of the ubiquitin-proteasome system in planta.
We are proud to announce that Ryan Buchner, a Shabek Lab undergraduate student researcher, was awarded the Spring 2020 Provost's Undergraduate Fellowship (PUF) from the UC Davis Undergraduate Research Center!
Natalie Hamada is awarded with the NIH T32 MCB training grant (with Dr. Nitzan Shabek) . This award will fund Natalie’s PhD program and research in the lab focusing on plant ubiquitin system.
Angelica Guercio has won a 2020-2021 Summer GSR Award - Integrative Genetics & Genomics Graduate Group’s. Angelica will continue her PhD studies on plant receptors sensing mechanisms; and will initiate the development of advanced integrated computational strategy to using Virtual Reality tools.
Isabella Glenn (Izzy), our undergrad researcher, has been selected to be a Kevin Gardner Research Scholar as part of the College of Biological Science Dean's Circle Summer Undergraduate Research Program. This fellowship will help Izzy to continue her research in the Shabek Lab during the summer.
Prof. Shabek receives the 2020 UC Davis Early Career Faculty Award for Innovation and Creativity. The award was established to honor and support the advances of outstanding tenure-track faculty members early in their careers. Read more about it: www.ucdavis.edu/news/innovation-award
Read the #2 Plant Physiology article based on number of mentions during the past month. With 29 mentions: UPDATE: Structural Aspects of Plant Hormone Signal Perception and Regulation by Ubiquitin Ligases @ShabekLab #Receptors #Signaling #PlantBiology https://t.co/ErksEAJLGi pic.twitter.com/vjK2pAUIFx— Plant Physiology (@PlantPhys) February 3, 2020 The lab's paper titled "Structural Aspects of Plant Hormone Signal Perception and…Read More
The Shabek lab got its first taste of autumn at the annual College of Biological Sciences Dean's Fall Welcome. This year's event welcomed over 600 incoming freshmen and transfer students from all majors throughout the college to UC Davis. Students were able to learn about a few of the many clubs, departments, and research activities…Read More
Come learn more about our research on plant hormone signaling at Plant Biology 2019 in San Jose, CA from August 3-7. Dr. Shabek will be presenting his talk titled "Structural plasticity of ubiquitin ligase complex in strigolactone signaling" in concurrent symposium 29. We hope to see you there!
Nitzan recently traveled to Paris to attend the International Plant Growth Substances Association (IPGSA) annual meeting, where he gave a plenary session on strigolactone sensing and metabolism by the ubiquitin ligase.
Congratulations to Isabella Glenn, an undergraduate student researcher in the Shabek lab, for being awarded a TGIF grant from UC Davis! TGIF, The Green Initiative Fund, supports student-led projects that aim to improve sustainability on campus and beyond. The TGIF grant will provide funds to enable her to perform her research in our lab. Way…Read More
We are proud to announce that three Shabek Lab undergraduate student researchers were awarded the Spring 2019 Provost's Undergraduate Fellowship (PUF) from the UC Davis Undergraduate Research Center! These competitive fellowships enable students to pursue research or creative activities under the guidance of UC Davis faculty members. Congratulations to Avalon Miller, Isabella Glenn, and Sam…Read More
Congratulations to Alex Kehl, an undergraduate student researcher in the Shabek lab, for being accepted into the UC Davis Maximizing Access to Research Careers/Biology Scholars Advanced Research Program (MARC/BSHARP)! The MARC/BSHARP program provides support and intensive research experience to exceptional undergraduate students from disadvantaged or underrepresented backgrounds. As part of this program, Alex will be…Read More
Congratulations to Dr. Shabek and the Zheng lab at UW on their paper “Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase,” published today in Cell Discovery (Nature).
Dr. Shabek’s work demonstrating structural plasticity of the D3–D14 ubiquitin ligase in strigolactone signaling is published in Nature! These findings reveal how D3 can utilize two distinct structural states to control strigolactone signaling. In its closed form, D3 binds to inactive D14. However, in its open conformation, D3 binds to hormone-bound D14 to enable strigolactone…Read More
