• Our paper is published in Nature Communications

    Our paper is published in Nature Communications

    Congratulations to Malathy Palayam, our postdoc and the Shabek lab for a wonderful paper! Check out our study on the mechanisms of strigolactone catabolism is now out in Nature Communications. Structural Insights into Strigolactone Catabolism by Carboxylesterases Reveal a Conserved Conformational Regulation. Nature Communications.LINK Palayam, M., Yan, L., Nagalakshmi, U., Gilio, AK., Cornu, D., Boyer,…Read More
  • Our new study is published in New Phytologist!

    Our new study is published in New Phytologist!

    Our research is published in New Phytologist today! Using TurboID (proximity labeling) transgenic lines expressing ubiquitin ligase module, we revealed their protein interactome in planta. Sun, F., Hamada, N., Montes-Serey, C., Li, Y., Meier, ND., Walley, JW., Dinesh-Kumar, SP*., and Shabek, N.* (2024) TurboID-Based Proteomic Profiling Reveals Proxitome of ASK1 and CUL1 of the SCF…Read More
  • Our new study is out in JBC!

    Our new study is out in JBC!

    Our new paper is out – on new structural insights into rice KAI2 receptor and functional implications for perception and signal transduction. Published in Published in Journal of Biological Chemistry: Guercio, AM., Gilio, AK., Pawlak, J., and Shabek, N. (2024). LINK
  • Katherine received the Summer GSR Award & NIH T32 Award

    Katherine received the Summer GSR Award & NIH T32 Award

      Congratulations to Katherine Hand, our PhD student, for receiving the 2024 Summer Graduate Student Researcher Award! 🥇 This award supports graduate research in engineering, computer sciences, and disciplines with engineering-related applications and methods. Additionally, Katherine has been selected to receive the NIH eMCB T32 training grant! We are proud of you, Katherine. Well done!…Read More
  • Darian DeBortoli received the 2024 CBS Undergraduate Research Fellowship

    Darian DeBortoli received the 2024 CBS Undergraduate Research Fellowship

    Congratulations to Darian DeBortoli, Shabek Lab undergraduate researchers, have been awarded the 2024 College of Biological Science Undergraduate Researcher Summer Fellowship! Well deserved!
  • Katherine received the 2024 Elsie Taylor Stocking Memorial Fellowship

    Katherine received the 2024 Elsie Taylor Stocking Memorial Fellowship

    Congratulations to Katherine Hand (our PhD student), for receiving the 2024 Elsie Taylor Stocking Memorial Fellowship!!! The Stocking Memorial Fellowship supports outstanding graduate students in studies and research in plants. We’re proud of you Katherine!
  • Our collaborative paper was highlighted in Nature Plants

    Our collaborative paper was highlighted in Nature Plants

    Our research was highlighted in Nature Plants: A smoke receptor for volatile signalling  
  • Our collaborative study is published in SCIENCE!!!

    Our collaborative study is published in SCIENCE!!!

    Congratulations to the Shabek Lab especially Angelica and Fuai – Our NSF funded research with Dudareva group at Purdue University is now published in Science – more discoveries on KAI2 signaling pathway:Volatile communication in plants relies on a KAI2-mediated signaling pathway.
  • Congratulations to Angelica Guercio on the successful completion of her Ph.D.

    Congratulations to Angelica Guercio on the successful completion of her Ph.D.

    Hats off to Dr. Angelica Guercio, the latest Ph.D. graduate from our lab! Congratulations on this remarkable well-deserved achievement! Proud of you!
  • Our new paper is out in New Phytologist!

    Our new paper is out in New Phytologist!

    Our new paper on new role of the C-terminal of SCF-D3/MAX2 ubiquitin ligase in KAI2-mediated signaling. Published in New Phytologist: Tal, L., Guercio, AM., Varshney, K., Young, A., Gutjahr, C., and Shabek, N. (2023). LINK
  • Angelica received the Best Poster Award in 2023 GRC Meeting

    Angelica received the Best Poster Award in 2023 GRC Meeting

    Angelica has been honored with the Best Poster Award at the 2023 Plant Proteolysis – Gordon Research Conference in Rhode Island
  • Natalie received the USDA-NIFA fellowship

    Natalie received the USDA-NIFA fellowship

    Congratulations, Natalie!!! For receiving the prestigious USDA – NIFA predoctoral fellowship that will sponsor her research in the next two years.
  • Fuai received the Outstanding Postdoc Award!

    Fuai received the Outstanding Postdoc Award!

    Our postdoc, Dr. Fuai Sun, is the recipient of the 2023 Plant Biology Chair’s Outstanding Postdoctoral Fellow Award. So well deserved, keep it up!
  • Angelica receives the Dean’s Grad Students Mentoring Award

    Angelica receives the Dean’s Grad Students Mentoring Award

    Congratulations, Angelica!!! The recipient of the 2023 Dean’s Grad Students Mentoring Award. For her outstanding devotion to train & mentor undergrads and junior researchers in the lab.
  • Congrats to our postdoc Dr. Lior Tal for starting her own lab!

    Congrats to our postdoc Dr. Lior Tal for starting her own lab!

    Congratulations to Dr. Lior Tal, one of our lab’s first postoctoral fellows (since 2019), for landing a PI/Assistant Professor position and will start the Tal Lab at Tel Aviv University (Plant Sciences) in Israel! Proud of you, well done and good luck, Lior!
  • JSB – the Journal Cover Page featuring our BAM8 paper.

    JSB – the Journal Cover Page featuring our BAM8 paper.

    Congratulations to the Shabek lab (Fuai and Malathy) recent publication – our Cover Page (credits to Dr. Shabek:-) has been selected as the cover page for September 2022 Volume of Journal of Structural Biology.
  • DOE Award to the Shabek lab

    DOE Award to the Shabek lab

    Congratulations!!! The Shabek lab just received a huge grant from the Department of Energy (DOE) – Biological and Environmental Research (BER) division. This funds will support our lab in collaboration with Justin Walley group (Iowa State U) and Andrew Groover (USDA Forest Services) to investigate the ubiquitin system in trees and drought response using multiomics…Read More
  • Our new paper is out –  Role of E3 Ligases in Chloroplasts

    Our new paper is out – Role of E3 Ligases in Chloroplasts

    Katherine Hand and Dr. Nitzan Shabek’s new paper is now published in International Journal of molecular Sciences. We highlighted recent studies that reveal new function of E3 ubiquitin ligases and their roles in chloroplast function.  
  • New NSF grant to the Shabek Lab!!!

    New NSF grant to the Shabek Lab!!!

    Congratulation on new funded project!!! Together with Natalia Doudareva from Purdue University, Dr. Shabek received $1.5M to study new hormone-like pathway. This would be our third NSF Award in two years!!
  • Our new paper is out: on the structure of maize BZR1-type β-amylase and noncatalytic adaptation!

    Our new paper is out: on the structure of maize BZR1-type β-amylase and noncatalytic adaptation!

    Congratulations to Drs. Fuai Sun and Malathy Palayam for the new publication in Journal of Structural Biology. This study takes a leap towards the understanding of the molecular architecture of catalytically inactive plant β-Amylase (BAM) proteins that play an essential role in growth, development, stress response, and hormone regulation.
  • Natalie received the 2022-23 Summer GSR Award!

    Natalie received the 2022-23 Summer GSR Award!

    Congratulations!!! Natalie Hamada has won the 2022-2023 Summer Graduate Student Researcher (GSR) Fellowship Award . Natalie will continue her PhD studies on the function of ubiquitin ligase in plant immunity, and will initiate the development of advanced integrated computational strategy to study protein-small molecule interactions using Virtual Reality tools.
  • Dr. Shabek received the Chancellor’s Award for Excellence in Mentoring Undergrad Research

    Dr. Shabek received the Chancellor’s Award for Excellence in Mentoring Undergrad Research

    Prof. Shabek is the recipient of the 2022 Chancellor’s Award for Excellence in Mentoring Undergraduate Research
  • Katherine Hand received Honorable Mention – Chancellor’s Award

    Katherine Hand received Honorable Mention – Chancellor’s Award

    Congratulations Katherine! For receiving Honorable Mention – Chancellor’s Award for Excellence in Undergraduate Research – in recognition of her excellent work as Undergraduate Researcher.
  • Vali Engles is awarded Provost’s Undergrad Fellowship

    Vali Engles is awarded Provost’s Undergrad Fellowship

    Congratulations Vali, Shabek Lab undergraduate student researcher, has been awarded the UC Davis Provost's Undergraduate Fellowship (PUF, 2022)!
  • Our new study is published in Nature Plants

    Our new study is published in Nature Plants

    New research from the Shabek laboratory at UC Davis unravels a new regulatory function of ubiquitin ligase in plant signalling. We combined structural biology, biochemistry and in planta CRISPR/Cas9 genome editing to show that the conformational switch in ASK1-D3/MAX2 CTH directly regulates the ubiquitin-mediated protein degradation process in strigolactone signaling pathway. We have also uncovered…Read More
  • Katherine and Shelly received the Dean’s Summer Undergraduate Research Fellowship

    Katherine and Shelly received the Dean’s Summer Undergraduate Research Fellowship

    Congratulations to Katherine Hand and Shelly Lee, Shabek Lab undergraduate researchers, have been awarded the 2022 College of Biological Science Undergraduate Researcher Summer Fellowship!
  • Our new paper on the structure function of KAI2s

    Our new paper on the structure function of KAI2s

    New research led by the Shabek laboratory at UC Davis together with multiple groups from Université Paris-Saclay and Technical University of Munich, revealed how molecular smoke detectors adapted to sense growth hormones in plants. https://www.nature.com/articles/s42003-022-03085-6 Highlighted in the news: UC Davis News EurekaAlert AAAS NSF Research News    
  • Angelica received the 2021 Elsie Taylor Stocking Memorial Fellowship

    Angelica received the 2021 Elsie Taylor Stocking Memorial Fellowship

    Congratulations to Angelica Guercio (our PhD student), for receiving the Stocking Fellowship!!! The Elsie Taylor Stocking Memorial Fellowship supports outstanding graduate students in studies and research in plants.
  • Dr. Nitzan Shabek received the 2021 Neish Award

    Dr. Nitzan Shabek received the 2021 Neish Award

    Dr. Shabek has been nominated and selected to receive the 2021  Arthur C. Neish Young Investigator Award from the Phytochemical Society of North America. The Neish Awards are given each year by the PSNA to outstanding early career scientists. Congratulations, Nitzan!!!
  • Dr. Nitzan Shabek received the NSF CAREER Award

    Dr. Nitzan Shabek received the NSF CAREER Award

    Congratulations!!! Our lab PI, Prof. Nitzan Shabek, has just awarded with the NSF most prestigious award, The NSF CAREER. This will help to fund our research for the next 5 years including innovative initiative in promoting STEM education. The NSF CAREER is described by the NSF as supporting those with the “potential to serve as…Read More
  • Structure basis of CRY2 is published

    Structure basis of CRY2 is published

    In a new study, published in Communications Biology (Nature press), the Shabek lab determined the molecular structure of light activated sensory domain of cryptochrome-2. This work was discussed in the press - UC Davis News & Aggie News & Eureka (AAAS) Science Times & Science Daily  
  • Dr. Nitzan Shabek Receives NSF EAGER Award

    Dr. Nitzan Shabek Receives NSF EAGER Award

    Dr. Nitzan Shabek, UC Davis, received the NSF EAGER award ($300,000). Together with Dr. Dinesh-Kumar's lab, they will study the molecular interactome of the ubiquitin-proteasome system in planta.
  • Ryan Buchner is awarded Provost’s Undergraduate Fellowship

    Ryan Buchner is awarded Provost’s Undergraduate Fellowship

    We are proud to announce that Ryan Buchner, a Shabek Lab undergraduate student researcher, was awarded the Spring 2020 Provost's Undergraduate Fellowship (PUF) from the UC Davis Undergraduate Research Center!
  • Natalie Hamada awarded NIH T32 MCB training grant

    Natalie Hamada awarded NIH T32 MCB training grant

    Natalie Hamada is awarded with the NIH T32 MCB training grant (with Dr. Nitzan Shabek) . This award will fund Natalie’s PhD program and research in the lab focusing on plant ubiquitin system.
  • Angelica Guercio wins 2020-2021 Summer GSR Award – Integrative Genetics & Genomics Graduate Group

    Angelica Guercio wins 2020-2021 Summer GSR Award – Integrative Genetics & Genomics Graduate Group

    Angelica Guercio has won a 2020-2021 Summer GSR Award - Integrative Genetics & Genomics Graduate Group’s. Angelica will continue her PhD studies on plant receptors sensing mechanisms; and will initiate the development of advanced integrated computational strategy to using Virtual Reality tools.
  • Isabella Glenn was selected to be a Kevin Gardner Research Scholar

    Isabella Glenn was selected to be a Kevin Gardner Research Scholar

    Isabella Glenn (Izzy), our undergrad researcher, has been selected to be a Kevin Gardner Research Scholar as part of the College of Biological Science Dean's Circle Summer Undergraduate Research Program. This fellowship will help Izzy to continue her research in the Shabek Lab during the summer.
  • Dr. Nitzan Shabek received the UC Davis Award for Innovation and Creativity

    Dr. Nitzan Shabek received the UC Davis Award for Innovation and Creativity

    Prof. Shabek receives the 2020 UC Davis Early Career Faculty Award for Innovation and Creativity. The award was established to honor and support the advances of outstanding tenure-track faculty members early in their careers. Read more about it: www.ucdavis.edu/news/innovation-award
  • Angelica gets honorable mention on NSF GFRP

    Angelica gets honorable mention on NSF GFRP

    Congratulations to our PhD student Angelica Guerico on receiving NSF GFRP Honorable Mention. We are so proud of you!
  • Ubiquitin ligases in hormone signaling published in Plant Physiology

    Ubiquitin ligases in hormone signaling published in Plant Physiology

    Read the #2 Plant Physiology article based on number of mentions during the past month. With 29 mentions: UPDATE: Structural Aspects of Plant Hormone Signal Perception and Regulation by Ubiquitin Ligases @ShabekLab #Receptors #Signaling #PlantBiology https://t.co/ErksEAJLGi pic.twitter.com/vjK2pAUIFx— Plant Physiology (@PlantPhys) February 3, 2020 The lab's paper titled "Structural Aspects of Plant Hormone Signal Perception and…Read More
  • The lab represents Plant Biology at the at the CBS Dean’s Fall Welcome

    The lab represents Plant Biology at the at the CBS Dean’s Fall Welcome

    The Shabek lab got its first taste of autumn at the annual College of Biological Sciences Dean's Fall Welcome. This year's event welcomed over 600 incoming freshmen and transfer students from all majors throughout the college to UC Davis. Students were able to learn about a few of the many clubs, departments, and research activities…Read More
  • Learn about our research at Plant Biology 2019

    Learn about our research at Plant Biology 2019

    Come learn more about our research on plant hormone signaling at Plant Biology 2019 in San Jose, CA from August 3-7. Dr. Shabek will be presenting his talk titled "Structural plasticity of ubiquitin ligase complex in strigolactone signaling" in concurrent symposium 29. We hope to see you there!
  • Nitzan presents at IPGSA in Paris

    Nitzan presents at IPGSA in Paris

    Nitzan recently traveled to Paris to attend the International Plant Growth Substances Association (IPGSA) annual meeting, where he gave a plenary session on strigolactone sensing and metabolism by the ubiquitin ligase.
  • Isabella Glenn awarded TGIF grant

    Isabella Glenn awarded TGIF grant

    Congratulations to Isabella Glenn, an undergraduate student researcher in the Shabek lab, for being awarded a TGIF grant from UC Davis! TGIF, The Green Initiative Fund, supports student-led projects that aim to improve sustainability on campus and beyond. The TGIF grant will provide funds to enable her to perform her research in our lab. Way…Read More
  • Avalon Miller, Isabella Glenn, and Sam Deck awarded Provost’s Undergraduate Fellowships

    Avalon Miller, Isabella Glenn, and Sam Deck awarded Provost’s Undergraduate Fellowships

    We are proud to announce that three Shabek Lab undergraduate student researchers were awarded the Spring 2019 Provost's Undergraduate Fellowship (PUF) from the UC Davis Undergraduate Research Center! These competitive fellowships enable students to pursue research or creative activities under the guidance of UC Davis faculty members. Congratulations to Avalon Miller, Isabella Glenn, and Sam…Read More
  • Alex Kehl awarded UC Davis MARC/BSHARP fellowship

    Alex Kehl awarded UC Davis MARC/BSHARP fellowship

    Congratulations to Alex Kehl, an undergraduate student researcher in the Shabek lab, for being accepted into the UC Davis Maximizing Access to Research Careers/Biology Scholars Advanced Research Program (MARC/BSHARP)! The MARC/BSHARP program provides support and intensive research experience to exceptional undergraduate students from disadvantaged or underrepresented backgrounds. As part of this program, Alex will be…Read More
  • Structure of DDA1-DDB1 Complex Published in Cell Discovery

    Structure of DDA1-DDB1 Complex Published in Cell Discovery

    Congratulations to Dr. Shabek and the Zheng lab at UW on their paper “Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase,” published today in Cell Discovery (Nature).
  • D3-D14 Ub Ligase Research Published in Nature

    D3-D14 Ub Ligase Research Published in Nature

    Dr. Shabek’s work demonstrating structural plasticity of the D3–D14 ubiquitin ligase in strigolactone signaling is published in Nature! These findings reveal how D3 can utilize two distinct structural states to control strigolactone signaling. In its closed form, D3 binds to inactive D14. However, in its open conformation, D3 binds to hormone-bound D14 to enable strigolactone…Read More

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