Exciting news from the Shabek Lab! Our new research article is now published in Nature Communications: Salicylic Acid Modulates Its Catabolic Enzymes via Proteasomal Degradation Linked to SCF-Associated Proximity Networks by Natalie Hamada, Malathy Palayam, Jacob Moe-Lange, Sun Hyun Chang, collaborators, and Nitzan Shabek. This study uncovers a new regulatory mechanism controlling the immune hormone…
Our new focused review article is now published in The Plant Journal: Ubiquitin Ligases in Plant Immunity: Structural Mechanisms and Signaling by Natalie Hamada, Katherine A. Hand, and Nitzan Shabek. This review explores how E3 ubiquitin ligases function as master regulators of plant immunity, controlling the stability and activity of receptors, kinases, transcription factors, and…
Our new review article is now online in Annual Review of Plant Biology: Structural Insights into Plant Hormone-Sensing Mechanisms by Sun Hyun Chang, Malathy Palayam, Katherine A. Hand, and Nitzan Shabek. This review highlights how plants detect hormones through remarkably diverse receptors and signaling systems that control growth, development, immunity, and environmental adaptation. Drawing on…
Molecular Insights into Volatile Organic Compound Sensing and Signaling in Plants by Matthew E. Bergman, Sun Hyun Chang, Benoît Boachon, Nitzan Shabek, and Natalia Dudareva. This review explores how plants sense volatile organic compounds (VOCs) released by neighboring plants, microbes, and the environment, revealing an emerging layer of plant communication. We highlight the receptors and…
Our new review article is now published in The Plant Journal: An Emerging Signaling Hub: KAI2 at the Nexus of Phytohormone Networks by Jacob Moe-Lange and Nitzan Shabek This work highlights how the receptor KAI2 has evolved from a niche player in seed germination to a central coordinator of plant growth, stress responses, and hormone…
🌟 We are excited to share that Edgar Cortes, incoming PBGG Master’s student in the Shabek Lab, has been awarded support through the NSF BEST (Bioindustrial Engineering for a Sustainable Tomorrow) training program. As part of this NSF-funded initiative, Edgar will receive fellowship support while pursuing his Master’s research in our lab. Congratulations, Edgar ,…
Congratulations to Katherine Hand, our PhD student, for receiving the 2025 Simon Chan Fellowship Award! 🥇
Congratulations to Malathy Palayam, our postdoc and the Shabek lab for a wonderful paper! Check out our study on the mechanisms of strigolactone catabolism is now out in Nature Communications. Structural Insights into Strigolactone Catabolism by Carboxylesterases Reveal a Conserved Conformational Regulation. Nature Communications.LINK Palayam, M., Yan, L., Nagalakshmi, U., Gilio, AK., Cornu, D., Boyer,…
Our new paper is out – on new structural insights into rice KAI2 receptor and functional implications for perception and signal transduction. Published in Published in Journal of Biological Chemistry: Guercio, AM., Gilio, AK., Pawlak, J., and Shabek, N. (2024). LINK
Congratulations to Darian DeBortoli, Shabek Lab undergraduate researchers, have been awarded the 2024 College of Biological Science Undergraduate Researcher Summer Fellowship! Well deserved!