Congratulations to the Shabek Lab, and especially to our collaborators with Katie Dehesh’s group (UC Riverside), for contributing to an exciting new study!
The work, “Bimodal retrograde signaling disrupts a suppressor network and activates a key transcriptional activator to direct stress responses,” uncovers how the plastidial metabolite MEcPP orchestrates stress-responsive gene expression. By dismantling suppressors (HAT1, TPL, and IMPα-9) and activating the transcription factor CAMTA3, MEcPP dynamically regulates gene networks central to the plant stress response. A great collaborative effort shedding new light on plastid-to-nucleus communication!