From atomic structures to organismal networks, we decode how life senses and responds

Living systems are constantly sensing their environment, responding to light, hormones, metabolites, and both abiotic and biotic stressors that orchestrate growth and development, defense and survival, and physiological adaptation.

How are these signals perceived and regulated through biosynthesis and proteolysis? Our research integrates cutting-edge approaches from biochemistry, structural biology, molecular and cellular biology, and plant sciences, together with genetics, proteomics, and interactome mapping, to decode sensing mechanisms and their corresponding signaling pathways.

Our overarching goal is to unravel these fundamental biological processes across multiple scales – from atomic structures to complex networks within organisms. By linking molecular detail to systems-level insight, we aim to expand fundamental knowledge and develop innovative strategies with transformative impact on agriculture, environmental sustainability, and human health.