{"id":75,"date":"2018-07-06T05:58:14","date_gmt":"2018-07-06T05:58:14","guid":{"rendered":"http:\/\/shabek-lab.ucdavis.edu\/?page_id=75"},"modified":"2026-05-06T20:43:26","modified_gmt":"2026-05-06T20:43:26","slug":"publications","status":"publish","type":"page","link":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<h3 style=\"text-align: center;\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shabek+N&amp;sort=date\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-1847 size-large\" src=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/03\/volumes_2024_lab-1024x137.jpg\" alt=\"\" width=\"1024\" height=\"137\" srcset=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/03\/volumes_2024_lab-1024x137.jpg 1024w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/03\/volumes_2024_lab-300x40.jpg 300w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/03\/volumes_2024_lab-768x103.jpg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/h3>\n<h3 style=\"text-align: center;\"><em><span style=\"color: #008000;\">Selected Publications and Preprints<\/span><\/em><\/h3>\n<p>Hamada, N., Palayam, M., Moe-Lange, J., Wyatt, G., Montes, C., Chang, S. H., Hu, A., Dinesh-Kumar, S. P., Zerbe, P., Walley, J. W., and <strong>Shabek, N<\/strong>. (2026) Salicylic acid modulates its catabolic enzymes via proteasomal degradation linked to SCF-associated proximity networks. <strong>Nature Communications<\/strong>. <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/www.nature.com\/articles\/s41467-026-72241-x\">LINK<\/a>\u00a0 \u00a0\u00a0<span style=\"color: #993366;\"><em>(<\/em><\/span><em><span style=\"color: #993366;\">mentioned in the<\/span> <a href=\"https:\/\/www.ucdavis.edu\/news\/plants-walk-fine-line-between-growth-and-defense\"><span style=\"color: #3366ff;\">News<\/span><\/a>)<\/em><\/span><\/p>\n<p>Hamada, N*., Hand, KA*., and <strong>Shabek, N.<\/strong> (2026) Ubiquitin ligases in plant immunity: structural mechanisms and signaling. <strong>The Plant Journal. <\/strong><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tpj.70846\">LINK<\/a><\/span><\/p>\n<p>Chang, S*., Palayam, M*., Hand, KA*., and <strong>Shabek, N.<\/strong> (2026) Structural Insights into Plant Hormone Sensing Mechanisms. <strong>Annual Reviews of Plant Biology. <\/strong><em>(VOL. 77). <\/em><a href=\"https:\/\/www.annualreviews.org\/content\/journals\/10.1146\/annurev-arplant-060625-095356\"><span style=\"color: #0000ff;\">LINK<\/span><\/a><\/p>\n<p>Bergman, M. E., Chang, S. H., Boachon, B., <strong>Shabek, N.,<\/strong> Dudareva, N. (2026) Perception by plant receptors: Molecular insights into volatile organic compound sensing. <strong>The Plant Journal.\u00a0<\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tpj.70789\"><span style=\"color: #0000ff;\">LINK<\/span><\/a><\/p>\n<p>Rodriguez-Zaccaro, F.D*., Moe-Lange, J*., Malik, S., Montes, C., Hamada, N., Groover, A.T., Walley, J.W.<em data-start=\"214\" data-end=\"230\">,<\/em>\u00a0<strong>Shabek, N.<\/strong> (2025) Dynamic ASK1 proximity networks uncover SCF-dependent and noncanonical roles in ABA and drought adaptation. <em data-start=\"346\" data-end=\"355\">bioRxiv<\/em> (preprint). <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.biorxiv.org\/content\/10.64898\/2025.12.22.696057v1\">LINK<\/a><\/span><\/p>\n<p>Moe-Lange, J.,\u00a0<strong>Shabek, N.<\/strong> (2025) An Emerging Signaling Hub: KAI2 at the Nexus of Phytohormone Networks.\u00a0<strong>The Plant Journal. <\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tpj.70609\"><span style=\"color: #0000ff;\">LINK<\/span><\/a><\/p>\n<p>Zeng, L., Guo, J., Palayam M., Rodriguez, C., Fernanda GM, M., Wang, Y., van de Ven, W., Pruneda-Paz, J., <strong>Shabek, N<\/strong>., Dehesh, K. (2025) Bimodal Retrograde Signaling Disrupts a Suppressor Network and Activates a Key Transcriptional Activator to Direct Stress Responses. <strong>The Plant Journal. <\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tpj.70478\"><span style=\"color: #3366ff;\"><span style=\"color: #0000ff;\">LINK<\/span><\/span><\/a><\/p>\n<p>Paries, M., Hobecker, K., Hernandez Luelmo, S., Binci, F., Guercio, A., Usl\u00e4nder, A., Cardoso, C., Si, Y., Wankner, L., Bashyal, S., Troycke, P., Br\u00fcckner, F., Pimprikar, P., <strong>Shabek, N<\/strong>., &amp; Gutjahr, C. (2025) The GRAS protein RAM1 interacts with WRI transcription factors to regulate plant genes required for arbuscule development and function. <strong>Proceedings of the Notational Academy of Sciences USA (PNAS)<\/strong><strong>.<\/strong> <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2427021122\">LINK<\/a><\/span><\/p>\n<p>Zhou, A., Kane, A., Wu, S., Wang, K., Santiago, M., Ishiguro, Y., Yoneyama, K., Palayam, M., <strong>Shabek, N<\/strong>., Xie, X., Nelson, DC., Li, Y. (2024). Evolution of Inter-organismal Strigolactone Biosynthesis in Seed Plants. <strong>Science.<\/strong> <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adp0779\"><span style=\"color: #3366ff;\">LINK<\/span><\/a><\/p>\n<p>Zeng, L., Guo, J., Palayam M., Rodriguez, C., Fernanda GM, M., Wang, Y., van de Ven, W., Pruneda-Paz, J., <strong>Shabek, N<\/strong>., Dehesh, K. (2024) Integrated Dual-Channel Retrograde Signaling Directs Stress Responses by Degrading the HAT1\/TPL\/IMP\u03b1-9 Suppressor Complex and Activating CAMTA3.<span style=\"color: #3366ff;\"> <a style=\"color: #3366ff;\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.08.29.610327v1\"><em>biorxiv<\/em><\/a><\/span><\/p>\n<p>Cowie, AE., Pereira, JE., DeGiovanni, A., McAndrew, RP., Palayam, M., Peek. JO., Muchilinski, AJ., Yoshikuni, Y., <strong>Shabek, N.,<\/strong> Adams, PD., Zerbe, P. (2024). The crystal structure of Grindelia robusta 7,13-copalyl diphosphate synthase reveals active site features controlling catalytic specificity. <strong>Journal of Biological Chemistry.<\/strong> <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021925824024232?via%3Dihub\"><span style=\"color: #3366ff;\">LINK<\/span><\/a><\/p>\n<p>Palayam, M., Yan, L., Nagalakshmi, U., Gilio, AK., Cornu, D., Boyer, FD., Dinesh-Kumar, SP., and <strong>Shabek, N.<\/strong> (2024) Structural Insights into Strigolactone Catabolism by Carboxylesterases Reveal a Conserved Conformational Regulation. <strong>Nature Communications.<\/strong> <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/rdcu.be\/dPGXH\">LINK<\/a>\u00a0 \u00a0<span style=\"color: #800000;\"><em>(<\/em><em>mentioned in the <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/www.ucdavis.edu\/news\/how-plants-become-bushy-or-not\">News<\/a><\/span> + more under <\/em><em><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/lab-in-the-media\/\">Media<\/a><\/span> )<\/em><\/span><\/span><\/p>\n<ul>\n<li><em>SPOTLIGHT &#8211; CELL ; Trends in Biochemical Sciences: The role of hydrolysis in perceiving and degrading the plant hormone strigolactones <a href=\"https:\/\/www.cell.com\/action\/showPdf?pii=S0968-0004%2824%2900223-8\"><span style=\"color: #339966;\">LINK<\/span><\/a><\/em><\/li>\n<\/ul>\n<p>Sun, F., Hamada, N., Montes-Serey, C., Li, Y., Meier, ND., Walley, JW., Dinesh-Kumar, SP*., and <strong>Shabek, N.<\/strong>* (2024) TurboID-Based Proteomic Profiling Reveals Proxitome of ASK1 and CUL1 of the SCF Ubiquitin Ligase in Plants. <strong>New Phytologist. <\/strong><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/nph.onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/nph.20014\">LINK<\/a> <span style=\"color: #993300;\">(selected for <a style=\"color: #993300;\" href=\"https:\/\/nph.onlinelibrary.wiley.com\/toc\/14698137\/2024\/244\/6\">New Phytologist<\/a> Cover Page, Volume 244; 6)<img decoding=\"async\" class=\"wp-image-2032 alignright\" src=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/11\/65EE3FAA-027B-47DD-8F1A-DF2300D1F531_1_105_c.jpeg\" alt=\"\" width=\"113\" height=\"149\" srcset=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/11\/65EE3FAA-027B-47DD-8F1A-DF2300D1F531_1_105_c.jpeg 772w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/11\/65EE3FAA-027B-47DD-8F1A-DF2300D1F531_1_105_c-228x300.jpeg 228w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2024\/11\/65EE3FAA-027B-47DD-8F1A-DF2300D1F531_1_105_c-768x1013.jpeg 768w\" sizes=\"(max-width: 113px) 100vw, 113px\" \/><\/span><\/span><\/p>\n<p>Guercio, AM., Gilio, KG., Pawlak, J., and<strong> Shabek, N.<\/strong> (2024). Structural insights into rice KAI2 receptor provide functional implications for perception and signal transduction. <strong>Journal of Biological Chemistry (JBC)<\/strong>. <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021925824020945?via%3Dihub\">LINK<\/a><\/span><\/p>\n<p>Eckardt, NA., [\u2026] <strong>Shabek N<\/strong>, et al. (2024). The lowdown on breakdown: Open questions in plant proteolysis. <strong>The Plant Cell. <\/strong><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/doi.org\/10.1093\/plcell\/koae193\">LINK<\/a><\/span><strong><em><br \/>\n<\/em><\/strong><\/p>\n<p><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author has-tooltip hasTooltip\" data-delta=\"1\" data-hasqtip=\"0\" aria-describedby=\"qtip-0\"><span class=\"nlm-surname\">Ganapathy<\/span><\/span>, J*.,<\/span> Hand, AK*., and <strong>Shabek, N.<\/strong> (2024). Analysis of 26S Proteasome Activity Across Arabidopsis Tissues. <strong>Plants<\/strong>. <a href=\"https:\/\/www.mdpi.com\/2223-7747\/13\/12\/1696\"><span style=\"color: #3366ff;\">LINK<\/span><\/a><\/p>\n<p>Stirling, AS., Guercio, AM, Patrick, RM., Huang, X., Bergman, M., Dwivedi, V., Kortbeek, RWJ., Liu, YK., Sun, F., Tao, WA., Li, Y., Boachon, B., <strong>Shabek, N.,<\/strong> and Dudareva, N. (2024). Volatile communication in plants relies on a KAI2-mediated signaling pathway. <strong>Science. <\/strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adl4685\"><span style=\"color: #3366ff;\">LINK<\/span><\/a><\/p>\n<p>Tal, L., Guercio, AM., Varshney, K., Young, A., Gutjahr, C., and <strong>Shabek, N.<\/strong> (2023). C-terminal conformational changes in SCF-D3\/MAX2 ubiquitin ligase are required for KAI2-mediated signaling<em><strong>. <\/strong><\/em><strong>New Phytologist. <\/strong><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/nph.onlinelibrary.wiley.com\/doi\/10.1111\/nph.19101\">LINK<\/a><\/span><\/p>\n<p><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author\" data-delta=\"2\"><span class=\"nlm-surname\">Guercio, AM*., Palayam, M*., and <strong>Shabek, N<\/strong> (2023). Strigolactones: Diversity, Perception, and Hydrolysis. <strong>Phytochemistry Reviews.<\/strong> <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11101-023-09853-4\">LINK<\/a><\/span><br \/>\n<\/span><\/span><\/span><\/p>\n<p id=\"page-title\" class=\"highwire-cite-title\">Sun, F*., Palayam, M*., and <strong>Shabek, N<\/strong> (2022). Structure of maize BZR1-type \u03b2-amylase BAM8 provides new insights into its noncatalytic adaptation. <strong>Journal of Structural Biology<\/strong><span style=\"color: #3366ff;\"> <a style=\"color: #3366ff;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1047847722000557?via%3Dihub\">LINK<\/a>\u00a0 <span style=\"color: #000000;\">and<\/span> <a style=\"color: #3366ff;\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.05.09.491193v1\">biorxiv<\/a> <span style=\"color: #800000;\">(selected for <a style=\"color: #800000;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1047847722000570\">JSB Cover Page<\/a>, Volume 214, 3)<img decoding=\"async\" class=\"wp-image-1582 alignright\" src=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2022\/09\/COVER_JSB1-769x1024.jpg\" alt=\"\" width=\"115\" height=\"153\" srcset=\"https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2022\/09\/COVER_JSB1-769x1024.jpg 769w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2022\/09\/COVER_JSB1-225x300.jpg 225w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2022\/09\/COVER_JSB1-768x1022.jpg 768w, https:\/\/shabek-lab.ucdavis.edu\/wp-content\/uploads\/2022\/09\/COVER_JSB1.jpg 1366w\" sizes=\"(max-width: 115px) 100vw, 115px\" \/><\/span> <\/span><\/p>\n<p>Tal, L., Palayam, M., Ron, M., Young, A., Britt, A., and <strong>Shabek, N<\/strong> (2022). A conformational switch in the SCF-D3\/MAX2 ubiquitin ligase facilitates strigolactone signaling. <strong>Nature Plants.<\/strong> <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/www.nature.com\/articles\/s41477-022-01145-7\"><span style=\"color: #0000ff;\">nature.com\/articles\/s41477-022-01145-7<\/span><\/a>\u00a0 <span style=\"color: #000000;\">Full text:<\/span> <a href=\"https:\/\/rdcu.be\/cMjK8\"><span style=\"color: #3366ff;\">LINK<\/span><\/a>\u00a0\u00a0\u00a0\u00a0 <em><span style=\"color: #000000;\">(<\/span><\/em><\/span><span style=\"color: #3366ff;\"><em><span style=\"color: #000000;\">mentioned in the <\/span><\/em><\/span><span style=\"color: #3366ff;\"><em><span style=\"color: #000000;\"><a href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/lab-in-the-media\/\"><span style=\"color: #800000;\">media<\/span><\/a> )<\/span><\/em><\/span><\/p>\n<p>Hand, AK., <strong>Shabek, N<\/strong> (2022). The Role of E3 Ubiquitin Ligases in Chloroplast Function. <strong>International Journal of Molecular Sciences. <\/strong><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/17\/9613\/htm\">LINK<\/a><\/span><\/p>\n<p>Trenner, J., Monaghan, J., Saeed, B., Quint, M*., <strong>Shabek, N<\/strong>*., and Trujillo, M<strong>*<\/strong> (2022). Evolution and Functions of Plant U-box proteins (PUBs): From protein quality control to signalling. <strong>Annual Reviews of Plant Biology.\u00a0<\/strong><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/doi.org\/10.1146\/annurev-arplant-102720-012310\">annurev-arplant-102720-012310<\/a><\/span><\/p>\n<p><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first has-tooltip hasTooltip\" data-delta=\"0\" data-hasqtip=\"4\" aria-describedby=\"qtip-4\"><span class=\"nlm-surname\">Martinez<\/span><\/span>, SE., <span class=\"highwire-citation-author has-tooltip hasTooltip\" data-delta=\"1\" data-hasqtip=\"1\"><span class=\"nlm-surname\">Conn<\/span><\/span>, CE., <span class=\"highwire-citation-author\" data-delta=\"2\"><span class=\"nlm-surname\">Guercio, AM.,<\/span><\/span> <span class=\"highwire-citation-author has-tooltip hasTooltip\" data-delta=\"3\" data-hasqtip=\"0\"><span class=\"nlm-surname\">Sepulveda, C.,<\/span><\/span> <span class=\"highwire-citation-author\" data-delta=\"4\"><span class=\"nlm-surname\">Fiscus<\/span><\/span>, CJ.,<span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"5\" data-hasqtip=\"3\"> <span class=\"nlm-surname\">Koenig<\/span><\/span>, <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"6\" data-hasqtip=\"2\"> <span class=\"title element-invisible\">D., <\/span><strong><span class=\"nlm-surname\">Shabek<\/span><\/strong><\/span><strong>, N.<\/strong>, <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"7\" data-hasqtip=\"5\" aria-describedby=\"qtip-5\"><span class=\"nlm-surname\">Nelson, DC (2022). <\/span><\/span><\/span><\/span>A <em>KARRIKIN INSENSITIVE2<\/em> paralog in lettuce mediates highly sensitive germination responses to karrikinolide. <strong>Plant Physiology. <\/strong><a href=\"https:\/\/academic.oup.com\/plphys\/advance-article\/doi\/10.1093\/plphys\/kiac328\/6637523?login=true\"><span style=\"color: #3366ff;\">LINK<\/span><\/a><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"7\" data-hasqtip=\"5\" aria-describedby=\"qtip-5\"><span class=\"nlm-surname\"><br \/>\n<\/span><\/span><\/span><\/p>\n<p>Guercio, AM., Salar, T., Cornu, D., Bendahmane, A., Boyer, FD., Rameau, C., Gutjahr, C., de Saint Germain, A<sup>*<\/sup>., and\u00a0 <strong>Shabek, N<\/strong><sup>*<\/sup> (2022). <span style=\"font-size: 12.0pt; line-height: 200%;\">Structural and Functional Analyses Explain Pea KAI2 Receptor Diversity and Reveal Stereoselective Catalysis During Signal Perception<\/span>. <span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"5\" data-hasqtip=\"2\" aria-describedby=\"qtip-2\"><span class=\"nlm-surname\"><strong>Communications Biology &#8211; Nature<\/strong>. <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.nature.com\/articles\/s42003-022-03085-6\">https:\/\/www.nature.com\/articles\/s42003-022-03085-6<\/a>\u00a0\u00a0 <\/span><\/span><\/span><\/span><em>(<\/em><em>mentioned in the <\/em><em><a href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/lab-in-the-media\/\">press<\/a> )<\/em><\/p>\n<p><span class=\"nlm-surname\">Yadav, B., Jogawat, A., <\/span>Lal, SK., Lakra, N., Mehta, S., <b>Shabek, N<\/b>., and Narayan OP (2021). Plant mineral transport systems and the potential for crop improvement. <b>Planta <\/b><a href=\"https:\/\/doi.org\/10.1007\/s00425-020-03551-7\"><span style=\"color: #3366ff;\">doi.org\/10.1007\/s00425-020-03551-7<\/span><\/a><\/p>\n<p><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first hw-author-orcid-logo-wrapper has-tooltip hasTooltip author-popup-hover\" data-delta=\"0\" data-hasqtip=\"1\" aria-describedby=\"qtip-1\"><span class=\"nlm-surname\">Palayam<\/span><\/span>, M., <span class=\"highwire-citation-author has-tooltip hasTooltip\" data-delta=\"1\" data-hasqtip=\"0\" aria-describedby=\"qtip-0\"><span class=\"nlm-surname\">Ganapathy<\/span><\/span>, J., <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"2\" data-hasqtip=\"3\" aria-describedby=\"qtip-3\"><span class=\"nlm-surname\">Guercio<\/span><\/span>, AM.,\u00a0<span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"3\" data-hasqtip=\"4\" aria-describedby=\"qtip-4\"><span class=\"nlm-surname\">Tal<\/span><\/span>, L., <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"4\" data-hasqtip=\"5\" aria-describedby=\"qtip-5\"><span class=\"nlm-surname\">Deck<\/span><\/span>, SL., and <span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"5\" data-hasqtip=\"2\" aria-describedby=\"qtip-2\"> <span class=\"nlm-surname\"><strong>Shabek, N<\/strong> (2021). Structural Insights into Photoactivation of Plant Cryptochrome-2.\u00a0<\/span><\/span><\/span> <span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"5\" data-hasqtip=\"2\" aria-describedby=\"qtip-2\"><span class=\"nlm-surname\"><strong>Communications Biology &#8211; Nature\u00a0<\/strong> <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.nature.com\/articles\/s42003-020-01531-x\">doi. 10.1038\/s42003-020-01531-x \/<\/a><\/span>\u00a0\u00a0\u00a0\u00a0 <em>(<\/em><em>mentioned in the <\/em><em><a href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/lab-in-the-media\/\">press<\/a> )<\/em><\/span><\/span><\/span><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author hw-author-orcid-logo-wrapper has-tooltip hasTooltip\" data-delta=\"5\" data-hasqtip=\"2\" aria-describedby=\"qtip-2\"><span class=\"nlm-surname\"><br \/>\n<\/span><\/span><\/span><\/p>\n<p>Sun, F., Ding, L., Feng, W., Cao, Y., Lu, F., Yang, Q., Li, W., Lu, Y., <strong>Shabek, N<\/strong>., Fu, F., and Yu, H (2020). Maize transcription factor ZmBES1\/BZR1-5 positively regulates kernel size. <strong>Journal of Experimental Botany <\/strong><a href=\"https:\/\/doi.org\/10.1093\/jxb\/eraa544\"><span style=\"color: #0000ff;\">doi.org\/10.1093\/jxb<\/span><\/a><\/p>\n<p>Kuppu, S., Marimuthu, M., Ron, M., Li, G., Huddleson, A., Siddeek, MH., Terry, J., Buchner, R., <strong>Shabek, N<\/strong>., Comai, L., and Britt, AB (2020). A variety of changes, including CRISPR\/Cas9 mediated deletions, in CENH3 lead to uniparental genome elimination and haploid induction on outcrossing. <strong>Plant Biotechnology Journal. <\/strong><a href=\"https:\/\/doi.org\/10.1111\/pbi.13365\"><span style=\"color: #0000ff;\">10.1111\/pbi.13365<\/span><\/a><\/p>\n<p>Tal, L., Anleu-Gil, MX., Guercio, AM., and <strong>Shabek, N<\/strong> (2020). Structural Aspects of Plant Hormone Signal Perception and Regulation by Ubiquitin Ligases. <strong>Plant Physiology.<\/strong> <a href=\"https:\/\/doi.org\/10.1104\/pp.19.01282\"><span style=\"color: #0000ff;\">10.1104\/pp.19.01282<\/span><\/a><\/p>\n<p><strong>Shabek, N<\/strong>., Ticchiarelli, F., Mao, H., Hinds, TR., Leyser, O. &amp; Zheng, N. (2018). Structural plasticity of D3-D14 Ub ligase in strigolactone signalling. <strong>Nature. <\/strong><a href=\"https:\/\/doi.org\/10.1038\/s41586-018-0743-5\"><span style=\"color: #0000ff;\">10.1038\/s41586-018-0743-5<\/span><\/a><\/p>\n<ul>\n<li><em>SPOTLIGHT &#8211; <\/em><em>Trends in Plant Science<\/em><em>. Binding or Hydrolysis? How Does the Strigolactone Receptor Work? (2019).<\/em> <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/doi.org\/10.1016\/j.tplants.2019.05.001\">10.1016\/j.tplants.2019.05.001<\/a><\/span><\/li>\n<li><em>M<\/em><em>entioned in the <\/em><em><a href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/lab-in-the-media\/\">press<\/a><br \/>\n<\/em><\/li>\n<\/ul>\n<p><strong>Shabek, N.<\/strong>, Ruble, J., Waston CJ, Garbutt KC, Hinds, TR., and Zheng, N. (2018). Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase. <strong>Nature &#8211; <\/strong><strong>Cell Discovery<\/strong><strong>. <\/strong><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/doi.org\/10.1038\/s41421-018-0064-8\">10.1038\/s41421-018-0064-8<\/a><\/span><\/p>\n<p>Zheng, N., <strong>Shabek, N.<\/strong> (2017).\u00a0 Ubiquitin ligases:\u00a0 structure, function, and regulation. <strong>Annual Reviews Biochemistry<\/strong>. <em>86, <\/em>129-157. <a href=\"https:\/\/doi.org\/10.1146\/annurev-biochem-060815-014922\"><span style=\"color: #0000ff;\">10.1146\/annurev-biochem-060815-014922<\/span><\/a><\/p>\n<p><strong>Shabek, N<\/strong>., Zheng, N. (2014). Plant ubiquitin ligases as signaling hubs. <strong>Nature Structure Molecular Biology<\/strong> <em>21,<\/em> 293-296. <a href=\"https:\/\/doi.org\/10.1038\/nsmb.2804\"><span style=\"color: #0000ff;\">10.1038\/nsmb.2804<\/span><\/a><\/p>\n<p>Zhou, F., Lin, Q., Zhu, L., Ren, Y., Zhou, K., <strong>Shabek, N<\/strong>.<strong>,<\/strong> <em>et al<\/em>. (2013). D14-SCF(D3)-dependent degradation of D53 regulates strigolactone signaling. <strong>Nature<\/strong>. <em>504<\/em>, 406-410. <a href=\"https:\/\/doi.org\/10.1038\/nature12878\"><span style=\"color: #0000ff;\">10.1038\/nature12878<\/span><\/a><\/p>\n<p><strong>Shabek, N<\/strong>., Herman-Bachinsky, Y., Buchsbaum, S., Lewinson, O., Haj-Yahya, M., Hejjaoui, M., Lashuel, HA., Sommer, T., Brik, A., and Ciechanover, A. (2012). The Size of the Proteasomal Substrate Determines Whether Its Degradation Will Be Mediated by Mono- or Polyubiquitylation. <strong>Mol Cell<\/strong>. <em>48,<\/em> 87-97. <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/doi.org\/10.1016\/j.molcel.2012.07.011\">10.1016\/j.molcel.2012.07.011<\/a>.<\/span><\/p>\n<ul>\n<li><em>RESEARCH HIGHLIGHT &#8211;\u00a0 Nature Reviews Molecular Cell Biology. Protein Metabolism: Length Matters (2012).<\/em> <a href=\"https:\/\/doi.org\/10.1038\/nrm3445\"><span style=\"color: #0000ff;\">doi.org\/10.1038\/nrm3445<\/span><\/a><\/li>\n<\/ul>\n<p>Braten O., <strong>Shabek, N<\/strong>., Kravtsova-Ivantsiv, Y., and Ciechanover, A. (2011).\u00a0 Generation of free ubiquitin chains is upregulated in stress, and facilitated by the HECT domain ubiquitin ligases, Ufd4 and Hul5. <strong>Biochem J<\/strong>. <em>444, <\/em>611-617. <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/doi.org\/10.1042\/BJ20111840\">10.1042\/BJ20111840<\/a><\/span><\/p>\n<p>Weissman, AM., <strong>Shabek, N.<\/strong>, and Ciechanover, A. (2011).\u00a0 The predator becomes the prey: regulation of the ubiquitin system by ubiquitylation and degradation. <strong>Nat Rev Mol Cell Biol<\/strong> <em>12<\/em>, 605-620. <a href=\"https:\/\/doi.org\/10.1038\/nrm3173\"><span style=\"color: #0000ff;\">10.1038\/nrm3173<\/span><\/a><\/p>\n<p><strong>Shabek, N.<\/strong>, Ciechanover, A. (2010). The degradation of ubiquitin: the fate of the cellular reaper. <strong>Cell Cycle<\/strong> <em>9<\/em>, 523-530. <a href=\"https:\/\/doi.org\/10.4161\/cc.9.3.11152\"><span style=\"color: #0000ff;\">10.4161\/cc.9.3.11152<\/span><\/a><\/p>\n<p><strong>Shabek, N.<\/strong>, Herman-Bachinsky, Y., and Ciechanover, A. (2009). Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation. <strong>PNAS<\/strong><em> 106<\/em>, 11907-11912. <a href=\"https:\/\/doi.org\/10.1073\/pnas.0905746106\"><span style=\"color: #0000ff;\">10.1073\/pnas.0905746106<\/span><\/a><\/p>\n<p><strong>Shabek, N<\/strong>., Iwai, K., and Ciechanover, A. (2007). Ubiquitin is degraded by the ubiquitin system as a monomer and as part of its conjugated target. <strong>Biochem Biophys Res Commun<\/strong><em> 363<\/em>, 425-431. <a href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2007.08.185\"><span style=\"color: #0000ff;\">10.1016\/j.bbrc.2007.08.185<\/span><\/a><\/p>\n<p><em>(<strong>*<\/strong> equal contribution)<\/em><\/p>\n<p><strong>Shabek full publications list in:<\/strong><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=nitzan+shabek\">Pubmed<\/a><\/p>\n<p><a href=\"https:\/\/scholar.google.com\/citations?user=o-1OmTgAAAAJ&amp;hl=en\">Google Scholar<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected Publications and Preprints Hamada, N., Palayam, M., Moe-Lange, J., Wyatt, G., Montes, C., Chang, S. H., Hu, A., Dinesh-Kumar, S. P., Zerbe, P., Walley, J. W., and Shabek, N. (2026) Salicylic acid modulates its catabolic enzymes via proteasomal degradation linked to SCF-associated proximity networks. Nature Communications. LINK\u00a0 \u00a0\u00a0(mentioned in the News) Hamada, N*., Hand,<span class=\"post-excerpt-end\">&hellip;<\/span><\/p>\n<p class=\"more-link\"><a href=\"https:\/\/shabek-lab.ucdavis.edu\/index.php\/publications\/\" class=\"themebutton\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":1752,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-75","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/pages\/75","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/comments?post=75"}],"version-history":[{"count":121,"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/pages\/75\/revisions"}],"predecessor-version":[{"id":2235,"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/pages\/75\/revisions\/2235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/media\/1752"}],"wp:attachment":[{"href":"https:\/\/shabek-lab.ucdavis.edu\/index.php\/wp-json\/wp\/v2\/media?parent=75"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}